After reading about The Powers That Be, my brother has come across an adult cartoon starring Kelsey Grammer that I'd never heard of. Gary the Rat! It's about a defense attorney that wakes up to discover that he's a rat. David Hyde Pierce, John Mahoney, and Ted Danson also appear in the credits. I think I'll have to watch it this evening. It started as a web cartoon before being made into a series. The web cartoons are on YouTube, and there's a link below to a website that has the full episodes.